LAVIV® is the first and only FDA-approved personalized cell therapy
to improve the look of smile lines.
Fibroblasts are a type of cell that produce collagen and play a key role in the continued health of your skin. Collagen provides firmness and structure to the skin and is essential in supporting the dermis (or middle layer) of the skin.
LAVIV® is made up of tens of millions of collagen-producing fibroblast cells that are cultivated from your own skin samples. Then your own living cells are injected superficially into the dermis (or middle layer) of the skin to improve the appearance of smile lines.
What makes LAVIV® unique?
LAVIV® is the first and only personalized cell therapy approved by the FDA to improve the look of smile lines. Your LAVIV™ treatment is unique because it is made from your own skin cells.
Is LAVIV® right for me?
LAVIV® may be right for you if you are an adult who desires an improved appearance in smile lines, a personalized cell therapy, and a treatment regimen that is clinically proven safe and effective. Be sure to talk to your health care provider to determine whether LAVIV™ is right for you.
How much does LAVIV® cost?
The cost of LAVIV® varies among LAVIV™ physicians and geographic regions. Talk to a Fibrocell-trained, board-certified dermatologist or plastic surgeon for more information about the cost of treatment.
Who should not use LAVIV®?
LAVIV® may not be right for you if you:
- Are allergic to the antibiotics gentamicin or amphotericin, dimethyl sulfoxide (DMSO), or things made from cattle (bovine). These ingredients are used during processing. Trace amounts may be present in LAVIV®.
- Have a skin infection on the face
- Seek immediate results
For complete safety information about LAVIV®, review the Full Prescribing Information.
How long will it take before I see results?
LAVIV® is administered in 3 separate treatment sessions, spaced at intervals of 3 to 6 weeks. Individual results vary.
What is the most important information I should know about LAVIV®?
LAVIV® is made especially for you from your own skin cells. Prior to injection, confirm with your physician that your information on the LAVIV® vial is correct. Your health care provider will check to see that the cells that come back from the manufacturer are yours. Using someone else’s cells can cause a serious reaction. Do not let anyone else use your LAVIV®. The process for making LAVIV® uses antibiotics (amphotericin and gentamicin), bovine serum (from cattle), and dimethyl sulfoxide (DMSO). If you are allergic to any of these, tell your health care provider. Do not use LAVIV® if you have a skin infection on your face because LAVIV® treatment can make the infection worse. Talk to your health care provider if you have any other infection.
How long do results last?
In clinical trials, results with LAVIV® were confirmed a full 6 months after the final LAVIV® treatment was administered. Effectiveness beyond 6 months has not been studied. Of course, individual results vary. Results beyond 6 months will be a topic of further study.
What are the most common side effects associated with LAVIV®?
The most common side effects with LAVIV® occur at the injection site.
These side effects include redness, bruising, swelling, pain, bleeding, lumps, irritation,
and itchiness. More than 80% of all side effects occurred at the injection site
and required no treatment. Eighty-six percent of all injection-site side effects went away within one week.
How is my LAVIV® Administered?
LAVIV® is injected directly into your smile lines using a small needle. This injection will take place in the office of a trained LAVIV® physician.
How many injections of LAVIV® will I receive?
The recommended treatment regimen is 3 separate LAVIV® treatments,
spaced at intervals of 3 to 6 weeks.
Where can I receive LAVIV®?
LAVIV® is currently available only through board-certified dermatologists and plastic surgeons who have completed a Fibrocell-approved training program. Find a listing of Fibrocell-certified LAVIV® physicians.
What are the ingredients in LAVIV®?
LAVIV® is made from your own collagen-producing cells (fibroblasts) and is composed of at least 98% pure fibroblasts placed in a mixture of water, sugars, vitamins, amino acids, and salts. Antibiotics (amphotericin and gentamicin), bovine serum (from cattle), and dimethyl sulfoxide (DMSO) are used during processing. Trace amounts of these ingredients may be present in LAVIV®.